光电-黄正
发布时间:2017-04-06 浏览次数: 378

姓名: 黄正

性别:男

出生年月:196111

职称:教授

研究方向: 光学工程 

学科专长:生物医生光子学                

E  MAILhuangz@fjnu.edu.cn  

通信地址:仓山区上三路8号    邮编:350007 

个人简介:

黄正博士长期以来在美国国家实验室、医学研究机构和高校从事生物医学光子学研究,期间与南开大学、山东大学、广州医学院、澳门大学和香港理工大学等国内高校联合开展国际合作,并以境外合作者身份参加多项国家级和省级科研项目,于2005年起开始与福建师范大学医学光电科学与技术重点实验室进行医学光子学技术研发领域的长期合作,积极推动国际前沿技术的转化和国内相关学科的发展。于2014年正式受聘福建师范大学全职教授,福建省引进高层次人才,现任福建师范大学医学光电技术研究中心主任。具有生物医学和光学等多学科的研究背景,是生物医学光子学、激光医学和光动力医学领域的知名学者。参与撰写和翻译中英文著作6部,发表英文论文120余篇,论文他引超过2500次。

  

教育经历:按时间倒排序,大专、学士、硕士、博士

1978/09–1983/07, 苏州医学院, 放射医学, 医学学士

1986/09–1989/07, 苏州医学院, 放射医学, 医学硕士

1991/11–1992/6 University of Surrey Environmental and Radiation Protection, 硕士班结业

1993/11–1997/10 King's College of London University Microbiology,博士

科研与学术工作经历:

2014/2-至今,福建师范大学,光电学院,教授,医学光电技术研究实验室 主任

2010/1-2013/12,福建师范大学,光电学院,讲座教授

2010/1-2014/2University of Colorado DenverCAPLabSenior Scientist 2006/1-2009/12University of Colorado DenverDepartment of Radiation OncologyAssistant Professor

2000/11-2005/12Denver HealthONE AllianceR&DStaff Medical Scientist

1997/11-2000/12National Renewable Energy Laboratory (NREL),博士后

学术兼职:

  

International Photodynamic Association (IPA) 理事 (2013 - )

European Platform of Photodynamic Medicine (EPPM) 理事 (2013 - )

Photodiagnosis and Photodynamic Therapy (PDPDT) 副主编 (SCI 收录,2010-)

International Society for Optics and Photonics (SPIE) 会员(2000 -

SPIE Photonics West – Photonics and Immune Responses 学术委员会委员、主委 (2003 - )

《激光生物学报》编委 (2016 - )

中华医学会激光医学分会肿瘤与光动力疗法小组 副组长 (2015 - )

中国光学学会生物医学光子学分会 委员 (2015 - )

中国生物医学工程学会生物医学光子学分会 委员 (2015 - )

研究方向:

生物医学光子学、生物组织结构与功能成像、光医学 - 技术和应用。

科研项目:

1. 国家自然科学基金面上项目, 81471703, 光动力疗法中肿瘤耐药性的靶向调控 , 2 015/01-2018/12, 70万,在研,主持

2. 国家自然科学基金面上项目, 61675044, 基于 光学相干成像评估移植肾脏功能研究 , 2017/01-2020/12, 60万,在研,主持

教学情况:5年讲授的研究生课程和指导学生参加创新创业比赛等

博士研究生:论文写作与学术交流

硕士研究生:论文写作与学术交流

论文著作:按时间倒排序,近5年发表的代表性学术论文、出版的学术专著、授权的发明专利和公开的政府咨询报告等;

期刊论文:

(1) 黄正,龚玮,詹振林,李伟军,陈郁,谢树森,活体移植肾脏的OCT光学监测新技术,光电子·激光,2016.7.15,(07):782~786

(2) 黄正,詹振林,邱海霞,邹健,Timothy C. Zhu, 实用临床光动力疗法剂量 学,中国激光医学杂志,2016251):34~60

(3) Zheng HuangYih-Chih HsuLi-Bo LiLuo-Wei WangXiao-Dong SongChristine M. N. YowChristine M. N. YowXia LeiAli I. MusaniRong-Cheng LuoBrian J. DayPhotodyanmic therapy of cancer-challenges of multidrug resistanceJournal of Innovative Optical Health Sciences20158 1):1530002

(4) K. GaoK.H. YuanB. ZhangZ.Q. Hu, Z. HuangSide-by-side comparison of photodynamic therapy and pulsed-dye laser treatment of port-wine stain birthmarksBritish Journal of Dermatology20131685):1040~1046

(5) 唐嘉铭, 黄正, 光声成像在光动力疗法研究中的应用 激光生物学报 2016 253):204~208

(6) 许建树,龚玮,邹健,谢树森,陈郁,黄正, 皮肤光学相干成像技术 中国激光医学杂志,2016.4.15,(02):97~102

(7) Ricky Wu Ellie Chu, ,Malini OlivoIp David C. Zheng Huang, W.Christine Yow An in vitro investigation of photodynamic efficacy of FosPeg (R) on human colon cancer cellsJournal of Innovative Optical Health Sciences201585):1540004

(8) Yuzhi Wang Kaihua YuanWei GongJian Zou, Zheng Huang. Optimizing light source for photodynamic therapy of port wine stain birthmarks Photonics & Lasers in Medicine2015.8.2044):375~376

(9) 雷霞,邱海霞,李福伦,黄正, 光动力疗法的免疫效应 中国医学文摘.皮肤科学,2015324):128~132

(10) Xia LeiBo LiuJinjin WuZheng Huang, A clinical study of photodynamic therapy for chronic skin ulcers in lower limbs infected with Pseudomonas aeruginosaArchives of Dermatological Research20153071):49 ~55

(11) Qing YeYang GengXian-Zeng ZhangWen-Lie ChenTian-Jie, TianShu-Sen XieZheng Huang  Mechanism study of laser cochleostomy-induced early hearing loss in a rat modelLasers in Medical Science2014292):73 9~747

(12) Yong-Gang QiangYong-Hua LiaoXiu-Ping ZhangJian Li Zheng Huang  Modulation of beta-adrenergic receptor in rat lung after gamma irradiationJournal of X-Ray Science and Technology2014222):165~173

(13) Li-Sheng LinLi-Na LiuHui-Fang HuangYuan-Zhong ChenBu-Hong LiZheng Huang, Characterizing fluorescence lifetime of nad(p)h in human leukemic myeloid cells and mononuclear cellsJournal of Innovative Optive Optical Health Science201364):1350042

(14) Lei TCPendyala S Scherrer LLi BGlazner GFHuang Z, Opti cal profiles of cathode ray tube and liquid crystal display monitors: implication in cutaneous phototoxicity in photodynamic therapyApplied Optics20135212):2711~2717

(15) Fei MiaoTing LvYunfeng Zhang, ,Xiuli WangHongwei (#) Zheng Huang Wang Induction of apoptosis in HPV16 E7 transfected human keratinocyte by ALA-mediated photodynamic therapyPhotodiagnosis and Photodynamic Therapy201 613205~210

(16) Shulian Wu Yunxia WangHui Li, Zheng Huang, Characterizing UVB-induced skin tumor process using optical coherence tomographyJournal of Innovative Optical Health Sciences201595):1650014

(17) 王玉芝,苑凯华,黄正, KTP激光与新型LED光源用于鲜红斑痣光动力治疗的 临床对比研究,实用医学杂志,20153124):38~41

(18) Ricky WuEllie ChuChuanshan XuC.W. IpZheng Huang, C Yow Effect of FosPeg (R) mediated photoactivation on P-gp/ABCB1 protein expression in human nasopharyngeal carcinoma cellsJournal of Innovative Optical Health Sciences201585):1550027

(19) Wang XJShi LTu QFWang HWZhang HYWang PRZhang LLHuang ZZhao FLuan HSWang XLTreating cutaneous squamous cell carcinoma using 5-aminolevulinic acid polylactic-co-glycolic acid nanoparticle-mediated photodynamic therapy in a mouse modelInternational Journal of Nanomedicine2 01510347~355

(20) Zhi-Xia FanLing-Lin ZhangHong-Wei WangPei-Ru Wang Zheng HuangXiu-Li WangTreatment of cutaneous lichen planus with ALA-mediated topical photodynamic therapyJournal of Innovative Optical Health Sciences201581 ):1540004

(21) Qiuqin ChenDongdong MaKaicong CaiSunjuan PanYuhua WangTiantian ZhangZheng HuangHongqin YangYiru Peng Effect of axial ligands on the photophysical properties of new silicon(IV) phthalocyaninesJournal of Coordination Chemistry2015684):732~740

(22) Bin ZhangTao-Hua ZhangQin LiKai-Hua YuanZhi-Qi HuZheng Huang,  Comparison of pulsed dye laser (PDL) and photodynamic therapy (PDT) for treatment of facial port-wine stain (PWS) birthmarks in pediatric patients.Photodiagnosis Photodyn Therapy2014114):491~497

(23) L. LiM. GillespieP. M. MrozL. A. MaierZ. Huang, p38 Mitogen-Activated Protein Kinase in beryllium-induced dendritic cell activation Human Immunology20147512):1155~1162

(24) Deng-Fu YangJia-Haur ChenChun-Pin ChiangJeng-Woe Lee, Zheng HuangChung-Ji LiuJunn-Liang ChangYih-Chih HsuImprove efficacy of topical ALA-PDT by calcipotriol through up-regulation of coproporphyrinogen oxidasePhotodiagnosis Photodyn Therapy2014113):331~341

(25) Jie JiLing-Lin ZhangHui-Lin DingHong-Wei WangZheng Huang,  Xiao-Xin WangPei-Ru WangXiu-Li Wang Comparison of 5-aminolevulinic acid photodynamic therapy and red light for treatment of photoagingPhotodiagnosis and Photodynamic Therapy2014112):118~121

(26) 雷霞,伍津津,黄正, 光动力对细菌生物膜的作用研究进展 中华皮肤科杂志,2014474):299~301

(27) Hai-yan ZhangJie JiYi-mei TanLing-lin ZhangXiao-jie WangPei-ru WangDe-gang YangLei ShiZheng HuangShun-ying ChenXiu-Li Wang Evaluation of 5-aminolevulinicacid-mediated photorejuvenation of neckskinPhotodiagnosis and Photodynamic Therapy2014111):498~509

(28) Deng-Fu YangJeng-Woei LeeHsin-Ming Chen Yih-Chih  Hsu, Zheng HuangMethotrexate enhances 5-aminolevulinic acid-mediated photodynamic  therapy-induced killing of human SCC4 cells by upregulation of coproporphyrinogen oxidaseJournal of the Formosan Medical Association2014 1132):88~93

(29) Wu RW Chu ES, ,Xu CSIp CWYow CM  (#) Huang Z (*) FosPeg (R) PDT alters the EBV miRNAs and LMP1 protein expression in EBV positive nasopharyngeal carcinoma cellsJournal of Photochemistry and Photobiology B-Biology2013127114~122

(30) Wang LWLin HLi ZSHetzel FLiu BLHuang Z, Effect of Photofrin-mediated photocytotoxicity on a panel of human pancreatic cancer cells.Photodiagnosis and Photodynamic Therapy2013103):244~251

(31) Wang HWLv TZhang LLLai YXTang LTang YCWang XL, Huang Z A prospective pilot study to evaluate combined topical photodynamic therapy and surgery for extramammary paget's diseaseLasers in Surgery and Medicine2 013455):296~301

(32) Hongwei WangJingjing LiTing LvQingfeng Tu Xiuli Wang, Zheng HuangTherapeutic and immune effects of 5-aminolevulinic acid photodynamic therapy on UVB-induced squamous cell carcinomas in hairless miceExperimental Dermatology2013225):362~363

(33) Lina LiuYingbin NieLisheng LinWeihua LiShusen Xie, Zheng Huang, Buhong LiPattern recognition of multiple excitation autofluorescence spectra for colon tissue classificationPhotodiagnosis Photodynamic Therapy2 013102):111~119

(34) Jian-Hua LiZhi-Qiang Chen Qi ZhanFu-Bin Ren, Zheng HuangJing-Ye LiuWu YueZhi WangIn vitro study of low intensity ultrasound combined with different doses of PDT: Effects on C6 glioma cellsOncology Letters201352):702~706

(35) Shi LWang XLZhao FLuan HTu QWang HWang HW Huang Z I n vitro evaluation of 5-aminolevulinic acid (ALA) loaded PLGA nanoparticlesIn ternational Journal of Manomedicine201382669~2676

(36) Liang ZXQiang YGLiao YHZhu XSZhang XPWang LP Huang Z In vivo mouse Tc-99m SPECT scans with bioluminescence imaging validationJournal of X-Ray Science and Technology2013211):85~91

(37) Min-Jie LiangQuan ZhouKan-Rong YangXiao-Ling YangJin FangWen-Li ChenZheng HuangIdentify changes of brain regional homogeneity in bipolar disorder and unipolar depression using resting-state FMRI.PLoS One2013812):e79999

  

学术专著:

Yih-Chih HsuZheng HuangClinical Photodynamic Therapy in the Chinese RegionCRC Press50002013.10.22

  

授权专利:

三项LED实用新型专利

  

在读研究生:

博士研究生:3

硕士研究生:6